Anatomic Pathology

Anatomic pathology focuses on analyzing the effects a potential NME (new molecular entity) or compound might have on a body's organs or tissue. Our necropsy, histology, and specialty pathology teams have been providing exceptional, solution-oriented service and high quality results for more than four decades. Our laboratories and anatomic pathologists are globally located, so we can support your preclinical, IND-enabling studies from a variety of facilities in North America, Europe and Asia.

Study Support

We offer standard and customizable necropsy and histology support for a number of preclinical and nonclinical studies:

Non-GLP lead optimization
Toxicology, including developmental and reproductive
Veterinary Pathology
Neurotoxicology
Metabolism
Carcinogenicity
Inhalation
Efficacy & animal disease models

Necropsy

GLP and non-GLP
Routine and specialized tissue collection / paradigms
Semen analysis

Histology

GLP and non-GLP
Tissue processing | paraffin; frozen; or plastic (glycol methacrylate or epoxy)
Embedding
Microtomy
Hematoxylin & Eosin staining
Special stains (Tinctorial)
Quality control: 100% slide check

Veterinary Pathology

Integrated interpretation / risk assessments
Pathologist consultation and peer review, including working groups
Expert opinions and reports
Regulatory consultation
Pathology data packaged in SEND format

Stand-Alone Services

We receive samples from animal studies not conducted at Covance to perform any histology or specialty service, with or without pathologist interpretation. Certain specialty pathology sites will also receive human tissue for analysis.

Fixed tissue
Frozen tissue
Paraffin blocks
Unstained slides
Stained slides

When you choose to outsource your histology, histopathology, or specialty pathology project to Covance you will work with experienced teams who are committed to driving your projects forward and also benefit from: