Anatomic Pathology

Anatomic pathology focuses on analyzing the effects a potential NME (new molecular entity) or compound might have on a body's organs or tissue. Our necropsy, histology, and specialty pathology teams have been providing exceptional, solution-oriented service and high quality results for more than four decades. Our laboratories and anatomic pathologists are globally located, so we can support your preclinical, IND-enabling studies from a variety of facilities in North America, Europe and Asia.

Study Support

We offer standard and customizable necropsy and histology support for a number of preclinical and nonclinical studies:

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Necropsy

  • GLP and non-GLP
  • Routine and specialized tissue collection / paradigms
  • Semen analysis

Histology

  • GLP and non-GLP
  • Tissue processing | paraffin; frozen; or plastic (glycol methacrylate or epoxy) 
  • Embedding
  • Microtomy
  • Hematoxylin & Eosin staining
  • Special stains (Tinctorial)
  • Quality control: 100% slide check

Veterinary Pathology

  • Integrated interpretation / risk assessments
  • Pathologist consultation and peer review, including working groups
  • Expert opinions and reports
  • Regulatory consultation
  • Pathology data packaged in SEND format

Stand-Alone Services

We receive samples from animal studies not conducted at Covance to perform any histology or specialty service, with or without pathologist interpretation. Certain specialty pathology sites will also receive human tissue for analysis.

  • Fixed tissue
  • Frozen tissue
  • Paraffin blocks
  • Unstained slides
  • Stained slides


When you choose to outsource your histology, histopathology, or specialty pathology project to Covance you will work with experienced teams who are committed to driving your projects forward and also benefit from:

  • Modern equipment and automation
  • High throughput capabilities
  • Co-ordinated sample logistics
  • Board certified pathologist support
  • Flexible reporting capabilities
  • Quality Assurance support
  • Archiving capabilities
histology lab

histology lab

Liver stained with Periodic Acid Schiff (PAS)
Periodic Acid Schiff, Liver
Kidney stained with Masson’s Trichrome
Masson’s Trichrome, Kidney
Large bowel stained with PAS and Alcian Blue
PAS/Alcian Blue, Bowel
Brain stained with Fluorojade C
Fluorojade C, Brain


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