Anatomic Pathology
Anatomic pathology focuses on analyzing the effects a potential NME (new molecular entity) or compound might have on a body's organs or tissue. Our necropsy, histology, and specialty pathology teams have been providing exceptional, solution-oriented service and high quality results for more than four decades. Our laboratories and anatomic pathologists are globally located, so we can support your preclinical, IND-enabling studies from a variety of facilities in North America, Europe and Asia.
Study Support
We offer standard and customizable necropsy and histology support for a number of preclinical and nonclinical studies:
- Non-GLP lead optimization
- Toxicology, including developmental and reproductive
- Veterinary Pathology
- Neurotoxicology
- Metabolism
- Carcinogenicity
- Inhalation
- Efficacy & animal disease models

Necropsy
- GLP and non-GLP
- Routine and specialized tissue collection / paradigms
- Semen analysis
Histology
- GLP and non-GLP
- Tissue processing | paraffin; frozen; or plastic (glycol methacrylate or epoxy)
- Embedding
- Microtomy
- Hematoxylin & Eosin staining
- Special stains (Tinctorial)
- Quality control: 100% slide check
Veterinary Pathology
- Integrated interpretation / risk assessments
- Pathologist consultation and peer review, including working groups
- Expert opinions and reports
- Regulatory consultation
- Pathology data packaged in SEND format
Stand-Alone Services
We receive samples from animal studies not conducted at Covance to perform any histology or specialty service, with or without pathologist interpretation. Certain specialty pathology sites will also receive human tissue for analysis.
- Fixed tissue
- Frozen tissue
- Paraffin blocks
- Unstained slides
- Stained slides
When you choose to outsource your histology, histopathology, or specialty pathology project to Covance you will work with experienced teams who are committed to driving your projects forward and also benefit from:
- Modern equipment and automation
- High throughput capabilities
- Co-ordinated sample logistics
- Board certified pathologist support
- Flexible reporting capabilities
- Quality Assurance support
- Archiving capabilities

