Anatomic Pathology

Anatomic pathology focuses on analyzing the effects a potential NME (new molecular entity) or compound might have on a body's organs or tissue. Our anatomic pathologists are globally located, so we can support your preclinical IND-enabling studies from a variety of facilities.

Anatomic Pathology Study Support

We offer standard and customizable necropsy and histology support for a number of preclinical and nonclinical studies:

Non-GLP lead optimization
Toxicology, including developmental and reproductive
Metabolism
Carcinogenicity
Inhalation
Efficacy models
Animal disease models

Necropsy

GLP and non-GLP
Routine and specialized tissue collection / paradigms
Semen analysis

Histology

GLP and non-GLP
Tissue processing | paraffin; frozen; or plastic (glycol methacrylate)
Embedding
Microtomy
Special stains

Veterinary Pathology

Integrated interpretation / risk assessments
Pathologist consultation and peer review, including working groups
Expert opinions and reports
Regulatory consultation

Stand-Alone Services

We receive samples from animal studies not conducted at Covance to perform any histology or specialty service, with or without pathologist interpretation. Certain Specialty Pathology sites will also receive human tissue for analysis.

Fixed tissue
Frozen tissue
Paraffin blocks
Unstained slides
Stained slides

Regulatory & Consulting Support

Peer reviewed pathology report to reach consensus
Pathology data packaged in SEND format