In Vivo Pharmacology Efficacy Models

In vivo pharmacology, the study of the biological effects of a compound in a living organism, gives you insight into how well your compound might be able to treat your targeted disease area. With hundreds of lead optimization pharmacology models and customized efficacy models for diseases, including oncology, immuno-oncology, cardiovascular, dermal, respiratory, immunology, fibrosis and renal, we can help you understand your drug's profile quickly and comprehensively.

Designing, Validating & Analyzing Hundreds of Efficacy Models

Access hundreds of validated lead optimization or custom efficacy models to help you determine the right profile for your disease indication.

Below are some of the more common therapeutic areas we work with: 

In vivo testing by a Covance research associate working using a microscope during an in vivo pharmacology project.

In Vivo Pharmacology Efficacy Models

In Vitro Models

  • Anxiety
  • Bone
  • Cardiovascular
  • CNS
  • Dermal
  • Gastrointestinal
  • Infectious disease
  • Immunogenicity
  • Metabolic
  • Oncology / Tumor models
  • Pain
  • Pulmonary arterial hypertension
  • Renal
  • Respiratory disease
  • Models of drug penetration across cornea and sclera 
  • Bovine Corneal Opacity and Permeability (BCOP) 
  • Melanin binding using ocular (not synthetic) melanin 
  • Pharmacokinetics & Distribution

Our nonclinical imaging has generated significant utility, and we are working on cutting-edge applications of pharmaco-imaging across many therapeutic areas.