In Vitro Metabolism
- Induction | Inhibition | Reaction Phenotyping
- Metabolic Stability
- Transporter Interactions & DDIs
- Protein Binding (PBB; plasma, etc.)
Better predict pharmacokinetic (PK) and drug-drug interactions (DDIs) with DMPK/ADME studies and computational modeling on your compound, prior to clinical trials, to move quickly from discovery to development.
Consider the integration possibilities between your preclinical and clinical studies
As an integrated preclinical & clinical CRO, we can offer you connected insights between your nonclinical pharmacology work and your clinical pharmacology studies and clinical trials.
For example, some PBPK pharmacometrics have been accepted in lieu of clinical DDI studies.
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