Search

By Industry Solutions (2)
By Phase (1)
By Molecule Type (1)
By Therapeutic Area (3)
Covance Events (9)
Geography (3)
Keywords (10)

Filters

Showing results 561 - 576 of 91813 for .

Showing results 561 - 576 of 91813 for .

NHP Poster Booklet
Primate Symposium 2010
Advances in Animal Welfare and Scientific Outcomes of the Bile Duct Cannulated Rat Model Utilised in ADME Studies
LASA 2016 -- Rats are typically the rodent species of choice for investigating the absorption, distribution, metabolism and excretion of new chemical entities. Since rats lack a gall bladder, they are an ideal model for investigating continuous biliary excretion and biotransformation in this common toxicological species. The design and implementation of a modified tail cuff and cannula system introduced at Covance permits the animal's own bile to be re-routed back into the duodenum during...