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Showing results 545 - 560 of 91813 for .

Showing results 545 - 560 of 91813 for .

Social Housing Solutions
Social Housing Solutions
A Novel Approach to Conducting Dog Metabolism Studies Allowing Dogs to be Pair Housed - Enhancing Welfare and Science
DMDG 2016 -- Currently, metabolism cages for the purposes of conducting ADME studies, enabling an "excretion balance" scientific objective to be met, involve single housing of animals. Even though such metabolism cages have limitations for animal welfare, they have been largely unchanged for 25-30 years. The improvement of animal welfare is a focus area at both Novo Nordisk and Covance, and therefore in joint collaboration, a metabolism cage for pair housing was designed to improve welfare...
Characterization of a Rabbit Model of Choroidal Neovascularization (CNV) and its Treatment with Lucentis®
ARVO 2017 -- The current best practice for evaluation of the efficacy of treatments for age-related macular degeneration (AMD) is a laser-induced choroidal neovascularization (CNV) model in nonhuman primates (NHP). It has been widely used to confirm efficacy of therapeutic agents such as Lucentis® and Eylea®. This model has been a useful tool in drug development, and other models are currently being reported with other species. However, there are limitations of this model in NHP. The...