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Showing results 401 - 416 of 91813 for .

Showing results 401 - 416 of 91813 for .

May 2017 Rabbit Health Monitoring Status Report - Monthly
May 2017 Rabbit Health Monitoring Status Report - Monthly
Effects of Sedation by Acepromazine on Routine Clinical Pathology Parameters and Intraocular Pressure in Rabbits
ACT 2016 -- It has been proposed by facility technical staff that administering a sedative dose of Acepromazine (ACE) to rabbits prior to blood sample collections can result in a calmer animal and a better blood collection experience for both the animals and the sample collection technician. ACE is a phenothiazine derivative antipsychotic drug and has a depressant effect on the central nervous system and therefore causes sedation, muscular relaxation, and a reduction in spontaneous...
The Effects of Standardisation of Primate Carers and Caging on Body Weight Gains During the Acclimation Period in a CRO
European Primate Veterinarians (EPV) 2015 Seminar - This poster shows how these changes in the unit have affected the body weight gains in newly arrived cynomolgus macaques over this period.
Evaluation of Serial Blood Sampling in the Minipig by Temporary Cannulation of the Saphenous Vein - Welfare and Study Design Refinements
LASA 2016 -- The minipig is a viable non-rodent species for safety testing of novel test substances, which is becoming increasingly popular as an alternative to dogs or primates. Information on the pharmacokinetics of a test substance forms an important part of this testing to predict its efficacy and the duration of its effects, to provide supportive data on the mechanisms of drug action, to predict side-effects, and for the extrapolation of results from laboratory animals to man. A...
MINIPIGS AS RESEARCH MODELS: TRENDS AND CONSIDERATIONS
For the better part of the last decade, the use of minipigs for nonclinical safety assessment studies has grown. Gain insight into the growing interest in minipigs as an alternative model in this interview with Covance thought leaders, Dr. Gerhard Weinbauer, Vice President of Global Developmental and Reproductive Toxicology and Tom Ervin, Study Director for Nonclinical Safety.