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Showing results 369 - 384 of 91813 for .

Showing results 369 - 384 of 91813 for .

A Preliminary Evaluation of the New Zealand White Rabbit Model for Zika Virus Infection during Gestation and Microcephaly in the Offspring
Teratology 2017 -- Zika virus is an infectious disease spread primarily through the bite of mosquitoes. It was recently reported that Zika virus also spreads from human to human through sexual contact and has been linked to Guillain-Barre syndrome. Current outbreaks of Zika virus disease are occurring in many countries and territories and there is an unmet need for effective prophylactic and therapeutic measures to control and/or cure the disease. There are currently no animal models to...
Prevention of Laser Photocoagulation Induced Choroidal Neovascularization Lesions by Intravitreal Doses of Ranibizumab in Cynomolgus Monkeys
ARVO 2009. Ocular-focused poster. To determine the lowest efficacious dose and steady-state trough concentration in cynomolgus monkeys that leads to 100% prevention of laser photocoagulation treatment-induced Grade IV choroidal neovascularization (CNV) lesions.
Hematology Hurdles -€“ Infusion of Biologics in Cynomolgus Monkeys
EuroTox 2016 -- Prolonged intravenous infusion (minimizing the risk of post dose hypersensitivity reactions) or continuous intravenous infusion (maintaining constant exposure) are increasingly common routes of administration for new biologic entities (NBE). For the majority of such NBEs, the quantification of leukocyte subpopulations by automated hematology analyzers is an important tool for the assessment of pharmacological and toxicological effects. This poster shows that a careful review...