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Showing results 193 - 208 of 91813 for .

Showing results 193 - 208 of 91813 for .

Positive Control Dose Response Curves in the In Vivo Comet Assay
Environmental Mutagenesis and Genomics Society 46th Annual Meeting, EMGS 2015
Detection of DNA Cross-Links in Rat Liver and Kidney in the In Vivo Alkaline Comet Assay
GTA 2016 -- In 2014, OECD published a test guideline for the conduct of the in vivo alkaline comet assay in rodents (OECD TG 489). The alkaline comet assay detects DNA strand breaks, which can be indicative of many genotoxic events; however, significant modifications to the test guideline protocol are required if DNA crosslinks are suspected as these cannot be reliably detected under standard conditions.