Preclinical and Clinical Ophthalmic CRO Solutions
Advance your ocular therapies with the only full-service CRO to offer personalized ophthalmic drug development services that span the entire continuum from discovery and preclinical to clinical trials and post-market follow-up studies. Whether you need support with anterior or posterior segments, rare ocular diseases, gene therapies, or ophthalmic devices and diagnostics, we know how to optimize your ophthalmic development.
Rely on our ophthalmic staff’s deep scientific and regulatory experience from delivering nearly 100 global, patient-centric ophthalmology clinical trials for emerging biotech companies over the last five years.
Work with renowned vision scientists as part of our exclusive 30+ year relationship with Ocular Services on Demand (OSOD) to handle your preclinical ocular needs and deliver specialized expertise in the ocular surface and anterior and posterior segments.
Enable intelligent patient recruitment with advanced data and increase your efficiencies with our established relationships with 1,400+ sites globally.
Experience counts when it comes to placing patients' needs at the forefront of your decisions and ensuring the success of your ophthalmology drug development program. Our expertise and insights at Covance have helped advance nearly 100 clinical ophthalmology studies over the last five years as we’ve provided flexible solutions for emerging and mid-sized biotech companies.
Get the cross-functional support and customized strategies you need to accelerate development timelines, anticipate and prevent issues and get your ophthalmic therapy into market. Together, our robust partnership can help your team improve patient lives, faster.
You may need toxicology (GLP and non-GLP), tissue distribution/pharmacokinetics (PK) and pharmacology to support your ophthalmology preclinical research. We understand the unique differences between the ocular surface, anterior segments and posterior segments and can offer our expertise in several ocular disease areas such as glaucoma, dry eye, uveitis, allergies and retinal diseases.
Your preclinical journey can also benefit from our experience in all drug/therapy classes and our OSOD partnership to provide ocular routes of administration for a number of models.
Working with Covance for your ophthalmology research also provides your team with access to our full service labs to address any needs for chemistry or bioanalytical services. Discover the difference of our integrated, comprehensive capabilities.
Our delivery is centered around unique clinical trial and testing solutions that are both patient-centric and flexibly aligned with your program’s needs.
- Accelerate patient recruitment and site identification – Access our de-identified lab results and patient intelligence data to help identify patient clusters to evaluate inclusion/exclusion criteria, pressure-test protocols and help locate patients near proven, experienced investigator sites that are part of our tracked and trusted network.
- Gain scientific and regulatory support – Extend your team’s capabilities with our regulatory and commercial guidance. Count on our extensive experience in assisting both small biotech and large pharmaceutical companies to help you achieve your strategic goals.
- Apply flexible, integrated delivery models – Whether you need to apply decentralized clinical trial approaches to mitigate delivery risks or take advantage of our full service or functional service provider (FSP) models, we can work together to optimize your delivery.
We design our delivery capabilities to match your preference and the needs of your project. Take advantage of these comprehensive full-service solutions while we track your project’s milestones and data with our Xcellerate® Informatics Suite.
Preclinical: Delivering expertise with Ocular Services on Demand (OSOD)
Advance your ophthalmic program with a consortium of more than 40 internationally respected vision scientists. Since 1999, Covance and OSOD have helped both emerging biotechs and large pharmaceutical companies work with vision science experts, such as board-certified veterinary ophthalmologists, electrophysiologists (for ERGs), veterinary and physician pathologists, clinicians, professional ocular photographers, as well as basic scientists in a wide range of ocular science areas.
Your team will receive unsurpassed vision science consulting – spanning study design, data acquisition/interpretation, clinical translation and regulatory strategies – and benefit from state-of-the-art instrumentation for comprehensive descriptive and functional evaluation of your endpoints.
Clinical: Optimizing your trials and focusing on the path to commercialization
Solutions for ocular surface and the anterior segment studies
Get expert support for your trials involving the ocular surface and the anterior segment. From cataracts, glaucoma and dry eye to allergy and inflammation, as well as contact and intraocular lens, and surgical and delivery devices, we can apply our lessons learned from supporting numerous studies across several key indications.
Solutions for the posterior segment studies
Rely on our retinal specialists to extend your team with experience in global studies spanning macular degeneration, diabetic retinopathy, retinitis pigmentosa, vitreomacular adhesion, proliferative vitreoretinopathy and inflammation.
We also offer unique expertise in ocular rare disease and ophthalmic cell and gene therapies.
Propel your complex clinical trial with a robust patient recruitment, engagement and retention strategy
With a strategy tailored to your ocular disease indication, our holistic approach starts with established site relationships to find the strongest, high-performing sites for your study and leverage existing agreements to expedite start up. We can also analyze our proprietary LabCorp de-identified data and filter by ICD10 diagnostic codes to geolocate patient populations closest to your sites. Working with our team of dedicated subject matter experts, you’ll get a comprehensive, data-driven site and patient engagement strategy that incorporates our best practices gleaned from our previous and current ophthalmology trial experience.
Once your trial is underway, you can rely on our ocular clinical trial management team to provide close communication and collaboration. We work to identify certified vendors that perform visual acuity assessments and central reads of the ocular imaging and use our highly flexible, in-house mClinical platform for electronic patient-reported outcome (ePRO) so you can receive high-quality data and stay connected to the progress of your program.
More than meets the eye: intelligent recruitment, inspiring science and integrated delivery
Advance your study with a CRO that provides clinical, scientific, regulatory and operational perspectives coupled with ophthalmic experienced teams that keep the patient at the forefront of your design decisions. From site selection to patient recruitment strategies and generation of quality data, we’re here to help you reduce the burden on patients and sites, mitigate risks and optimize your processes throughout your program.
Discover the difference of working with a dedicated partner that offers end-to-end drug development services. Together, we can find the best path forward for your ophthalmic product.