Articles

EOGRTS - What You Need to Know: Understand the Complexities and Overcome the Challenges for Your Substances

Some of the ingredients present in certain chemicals and agrochemicals can be harmful to people, animals and the environment. These substances are, therefore, tightly regulated across the world, and particularly in Europe. In 2001, the France-based Organization for Economic Co-operation and Development (OECD) imposed guideline 416, which required chemical companies to perform two-generation reproduction toxicity studies (TGRTS) on their new substances to provide data on the impact a substance can have on male and female reproductive systems and the growth and development of the offspring. In 2007, European Chemicals Agency (ECHA) and its REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) regulations required reproductive toxicity testing for new chemicals, and it adopted OECD 416 (2001). Prior to REACH, only substances that were suspected to have toxicity issues were tested.

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Articles
Chemical (Industrial)
EOGRTS
Toxicology
Toxicology (DART)