Toxicology and Safety Assessment
Services: Ocular Drug Development Services |
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The complexities of the eye pose unique challenges in the design of ocular drug development studies. Covance is committed to providing the specialized tools and techniques required for a diverse range of ocular study types in multiple species.
Covance has teamed up with the Comparative Ophthalmic Research Laboratories (CORL) located at the University of Wisconsin-Madison. CORL is a consortium of internationally respected vision scientists. The Covance/CORL alliance creates a unique and superior resource for ocular drug development--one that will not only increase your confidence in the success of your study but enable you to keep timelines and costs firmly in line.
All ophthalmic studies conducted at Covance are to GLP standards. CORL scientists participating in these studies receive the same GLP training required of all Covance study management personnel.
Covance and CORL offer the following ocular study capabilities: |
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 Corneal Endothelial Reading Center NEW
- Slit-lamp biomicroscopy and indirect ophthalmoscopy
- Multiple routes of ocular dosing, including intravitreal, sub-Tenon's and sub-retinal
- Tonometry
- Pachymetry
- Fundus photography and scoring
- Fluorescein angiography
- Electroretinography (full field and multi-focal)
- Optical coherence tomography
- Iris colorimetry
- Specular microscopy (contact and non-contact)
- Pharmacokinetic and ocular distribution studies
- Animal models of ocular disease (glaucoma and choroidal neovascularization)
- Pharmacologic efficacy models
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The Eyes Have It: A Look at Ocular Drug Development Studies
Brian Christian, PhD; Birgit Niggemann, MS: Craig Struble, PhD; and Chris Murphy, DVM; PhD
Covance Evolutions Newsletter
Volume 11, No. 1, April 2006
Download PDF |
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