Draw on the extensive Covance expertise and experience for special reproductive and developmental toxicology studies and techniques: 

Pharmacokinetics, toxicokinetics, pharmacodynamics:

  • Parental blood
  • Fetal blood (including very young gestational ages)
  • Fetal tissue
  • Amniotic fluid
  • Milk collection

Male reproduction evaluations:

  • Spermatogenesis evaluations
    • motility, total count and morphology
  • Spermatogenesis staging
  • Endocrinology Testicular volume (NHP)Testicular biopsy (NHP)
  • Prostate status (NHP)

Female reproduction evaluations:

  • Estrus determination
  • Histopathology
  • Endocrinology
  • Cycle monitoring

Neurobehavioral testing:

  • Spatial
  • Learning and memory
  • Functional operation battery

Infant/Pup evaluations:

  • Growth and behavior
  • Immune system development (NHP)
  • Nervous system development (NHP)
  • Body composition (NHP)
  • Bone development (NHP)

Fetal evaluations:

  • External examinations
  • Soft tissue examinations
  • Special histological evaluations (e.g. immune system development)
  • Skeletal examinations (double staining available)

Other techniques:

  • Endoscopy
  • Fluoroscopy
  • DEXA scanning
  • Laparoscopy


Download scientific posters on the following topics: