The protocols shown below are the standard protocols that we offer. Dosages, injection routes and timing can be adjusted as needed. We can also accommodate client-supplied custom protocols upon request.

It is highly recommended that your lab monitors the titer of antigen specific antibody throughout the study or that Covance performs ELISA screening on any pre-bleed, test bleed, production bleed or terminal bleed as proactive steps can be taken throughout the study to increase response to the antigen.

Animal Antigen Required Estimated Serum Volume* Rabbit Protein, 59 Day [Accelerated Protocol] 500 ug 70 mL Rabbit Protein, 77 Day 625 ug 110 mL Rabbit Protein, 84 Day 750 ug 95 mL Rabbit Protein, 118 Day — Standard Historically Successful 875 ug 120 mL Guinea Pig Protein, 115 Day 700 ug 19 mL Rat Protein, 118 Day 600 ug 15.5 mL Mouse Protein, 118 Day 400 ug 0.8 mL Goat / Sheep Protein, 118 Day 2.5 mg 1000 mL Chicken Protein, 118 Day 875 ug 18 mL**

Animal Antigen Required Estimated Serum Volume* Rabbit Peptide, 59 Day [Accelerated Protocol] 1.0 mg 70 mL Rabbit Peptide, 77 Day 2.0 mg 90 mL Rabbit Peptide, 84 Day 1.75 mg 95 mL Rabbit Peptide, 118 Day — Standard Historically Successful 2.0 mg 115 mL Guinea Pig Peptide, 115 Day 1.5 mg 19 mL Rat Peptide, 118 Day 1.5 mg 15.5 mL Mouse Peptide, 118 Day 0.8 mg 0.8 mL Goat / Sheep Peptide, 118 Day 7.0 mg 1000 mL Chicken Peptide, 118 Day 2.0 mg 18 mL**