Meet all your development needs with the wide range of animal health preclinical vaccine services from Covance:

  • Immunogenicity testing on formulated vaccine
  • Dose stability
    • thermostability, real time, accelerated and reconstitution stability
  • Dose response studies
  • Efficacy testing
    • vaccination and serology
    • infectious agent challenge (up to ABSL-2)
  • Development of potency testing for vaccine release
    • guinea pig potency
    • mouse potency
  • Safety studies - veterinary vaccines only
    • master seed safety - modified live vaccine agents
      • 10X dose
      • reversion to virulence
      • non-target species safety
    • master cell stock safety - gross pathology in target species
      • oncogenicity
      • tumorigenicity
    • vaccine safety - modified live, killed and recombinant subunit
      • single and repeat dose toxicity
      • overdose toxicity
        • 10 doses for modified live
        • 2 doses for killed
    • qualification and validation studies - batch/lot release studies
    • equivalency testing
    • lot to lot comparison
    • lots from different manufacturing sites
  • Field safety studies
    • 3 geographic locations
    • 100-200 animals/study, 20% targeted age
  • Safety and immunogenicity

Immunology Services

Tel: 800-345-4114
Tel: 717-336-4921
Fax: 717-336-3481

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Study Viewer

Study Viewer

Accreditations

  • AAALAC International Accredited
  • GLP Studies
  • OLAW Assured
  • USDA Research Registered