Use plasma protein binding and blood-cell partitioning services from Covance to assess your drug candidate's distribution within animals or humans. Assess in vitro and ex vivo protein binding and blood cell partitioning with Covance's routine techniques that include:
Equilibrium dialysis- for regulatory driven candidate development programs
Ultrafiltration – alternate technique for compounds with low non-specific binding
Blood cell partitioning- for in vitro and ex vivo assessments of RBC, WBC and platelet binding
Download a poster on Comparison of Conventional , 96-Well Plate and Rapid Equilibrium Dialysis (RED) Methodologies.