Determine oral membrane permeability with Caco-2 in vitro absorption studies from Covance. Caco-2 cell monolayers are an excellent model for oral permeability and the investigation of absorption mechanisms involving P-gp and BCRP. Let Covance determine:

• Apical to basolateral transport as a model for physiological absorption from the lumen
• Basolateral to apical transport as a model for exsorption and determination of efflux ratios
• Rank order of the absorption potential of your compounds