Procure GLP or GMP compliant physicochemical and biological techniques and state-of-the-art chromatographic, mass spectrometric, and electrophoretic instruments with Covance. Equipped as a full service provider for biotechnology products, Covance offers a comprehensive set of analytical techniques and services to fully characterize biomolecules.

Covance helps you determine:

  • Primary, secondary and tertiary structure
  • Confirm identity, purity, consistency of manufacture
  • Support formulation development and material compatibility


  • SDS-PAGE (reducing/non-reducing/native)
  • Chromatographic techniques of many types including:
    • reverse phase
    • ion exchange
    • size exclusion
    • affinity chromatography
  • Isoelectric focusing (IEF)
  • Electrophoretic (Western) blotting
  • Capillary electrophoresis (CE)
  • UV-visible spectroscopy
  • Fluorescence spectroscopy
  • Amino acid analysis
  • Electrospray mass spectrometry (ES-MS)
  • MALDI-ToF mass spectrometry
  • Peptide mapping (by LC or LC-ES MS)
  • Extinction coefficient determination
  • N-terminal sequencing
  • Immunochemistry assays
    • ELISA
    • Radioimmunoassay

Click to see Covance's Protein Chemistry Services.


Develop, characterize, test and validate with Covance, no matter what technique or molecule you're pursuing. Our experience covers a wide range of biomolecules, including: