Compound Analytes Species Matrix LLOQ-
ULOQ		 Validated
Sample
Vol. (mL)		 Method Anti-
coagulant
Adefovir Adefovir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Ritonavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
 
Amprenavir Amprenavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Indinavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Nelfinavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Ritonavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Saquinavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
 
Dapsone Dapsone Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Debrisoquine Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Mephenytoin Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Tolbutamide Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Theophylline Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
 
Debrisoquine Debrisoquine Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Dapsone Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Mephenytoin Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Tolbutamide Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Theophylline Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
 
Ethinyl Estradiol Ethinyl Estradiol Human P 2.50-500 pg/mL 0.500 LC-MS/MS 2
Norethindrone Human P 50.0-10,000 pg/mL 0.500 LC-MS/MS 2
 
IL-1β IL-1β Human S 15.0-5,000 pg/mL 0.200 ECL N
IL-6 Human S 15.0-5,000 pg/mL 0.200 ECL N
TNF-α Human S 15.0-5,000 pg/mL 0.200 ECL N
 
IL-6 IL-6 Human S 15.0-5,000 pg/mL 0.200 ECL N
IL-1β Human S 15.0-5,000 pg/mL 0.200 ECL N
TNF-α Human S 15.0-5,000 pg/mL 0.200 ECL N
 
Indinavir Indinavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Amprenavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Nelfinavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Ritonavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Saquinavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
 
Lopinavir Lopinavir Human P 20.0-20,000 ng/mL 0.100 LC-MS/MS 6
Ritonavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
 
Lopinavir Lopinavir Human P 20.0-20,000 ng/mL 0.050 LC-MS/MS 2
Ritonavir Human P 10.0-2,000 ng/mL 0.050 LC-MS/MS 2
 
Mephenytoin Mephenytoin Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Dapsone Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Debrisoquine Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Tolbutamide Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Theophylline Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
 
Nelfinavir Nelfinavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Amprenavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Indinavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Ritonavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Saquinavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
 
Norethindrone Norethindrone Human P 50.0-10,000 pg/mL 0.500 LC-MS/MS 2
Ethinyl Estradiol Human P 2.50-500 pg/mL 0.500 LC-MS/MS 2
 
Ritonavir Ritonavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Indinavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Nelfinavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Saquinavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Amprenavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
 
Ritonavir Ritonavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Amprenavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
 
Ritonavir Ritonavir Human P 10.0-2,000 ng/mL 0.050 LC-MS/MS 6
Lopinavir Human P 20.0-20,000 ng/mL 0.050 LC-MS/MS 6
 
Ritonavir Ritonavir Human P 10.0-2,000 ng/mL 0.050 LC-MS/MS 2
Lopinavir Human P 20.0-20,000 ng/mL 0.050 LC-MS/MS 2
 
Saquinavir Saquinavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Amprenavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Indinavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Nelfinavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
Ritonavir Human P 10.0-10,000 ng/mL 0.100 LC-MS/MS 6
 
Tenofovir Tenofovir Human P 1.00-200 ng/mL 0.100 LC-MS/MS 2
Adefovir Human P 1.00-200 ng/mL 0.100 LC-MS/MS 2
 
Tenofovir Tenofovir Human U 50.0-5,000 ng/mL 0.050 LC-MS/MS N
Adefovir Human U 50.0-5,000 ng/mL 0.050 LC-MS/MS N
 
Theophylline Theophylline Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Dapsone Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Debrisoquine Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Mephenytoin Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Tolbutamide Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
 
Tolbutamide Tolbutamide Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Theophylline Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Dapsone Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Debrisoquine Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
Mephenytoin Human P 5.00-2,000 ng/mL 0.100 LC-MS/MS 2
 
TNF-α TNF-α Human S 15.0-5,000 pg/mL 0.200 ECL N
IL-1β Human S 15.0-5,000 pg/mL 0.200 ECL N
IL-6 Human S 15.0-5,000 pg/mL 0.200 ECL N