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Development_VEGF signaling via VEGFR2 - generic cascades [score: 1 (0%)]
VEGF family of ligands and receptors is crucial for vascular development and
neovascularization in physiological and pathological processes in both embryo and adult.
VEGFR-2 is a high-affinity receptor for
VEGF-A. Activated VEGFR-2 can
activate p38 MAPK, PI3K reg class
IA/ ...
Development_VEGF signaling and activation [score: 1 (0%)]
The vascular endothelial growth factor (VEGF) family of ligands and receptors is
crucial for vascular development and neovascularization in physiological and pathological
processes in both embryo and adult [1]. VEGFs denote a family of homodimeric
glycoproteins that currently ...
Development_Prolactin receptor signaling [score: 1 (0%)]
Prolactin is a polypeptide hormone secreted by the
pituitary gland and to a lesser extent by numerous extrapituitary tissues. This hormone
affects a great amount of physiological processes [1]. Numerous biological
functions have been attributed to this hormone's ...
Apoptosis and survival_Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway [score: 1 (0%)]
The members of the tumour necrosis factor ligand family (TNFs) may induce both
apoptotic and anti-apoptotic pathways. TNFs transduces cellular responses through
activation of different TNF-receptors (TNFRs).
One important mechanism of cell survival is the activation of transcription of
different ...
Mucin expression in CF via TLRs, EGFR signaling pathways [score: 1 (0%)]
Cystic Fibrosis (CF) is a potentially lethal genetic disease that typically results in
the development of bronchial inflammation, bronchiectasis, the progressive loss of lung
function and ultimately death [1].
CF was initially called "mucoviscidosis" because of ...
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