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Regulatory Processes
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Protein Regulatory Pathways
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| Showing 1 - 9 out of 9 |
Result pages:
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DNA damage_ATM/ATR regulation of G1/S checkpoint [score: 1 (0%)]
DNA damage checkpoints are biochemical pathways that delay or arrest the cell cycle
progression in response to the DNA damage. All eukaryotic cells have four phases within
the cell cycle, G1, S, G2, and M, and one outside, G0 [1].
The G1/S checkpoint prevents cells ...
Development_TGF-beta receptor signaling [score: 1 (0%)]
Transforming growth factor beta (TGF-beta) signaling
controls diverse cellular processes, including cell proliferation, differentiation,
adhesion and migration [1], [2], [3].
TGF-beta 1 initiates ...
Development_VEGF signaling via VEGFR2 - generic cascades [score: 1 (0%)]
VEGF family of ligands and receptors is crucial for vascular development and
neovascularization in physiological and pathological processes in both embryo and adult.
VEGFR-2 is a high-affinity receptor for
VEGF-A. Activated VEGFR-2 can
activate p38 MAPK, PI3K reg class
IA/ ...
Development_VEGF signaling and activation [score: 1 (0%)]
The vascular endothelial growth factor (VEGF) family of ligands and receptors is
crucial for vascular development and neovascularization in physiological and pathological
processes in both embryo and adult [1]. VEGFs denote a family of homodimeric
glycoproteins that currently ...
Development_Prolactin receptor signaling [score: 1 (0%)]
Prolactin is a polypeptide hormone secreted by the
pituitary gland and to a lesser extent by numerous extrapituitary tissues. This hormone
affects a great amount of physiological processes [1]. Numerous biological
functions have been attributed to this hormone's ...
Apoptosis and survival_Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway [score: 1 (0%)]
The members of the tumour necrosis factor ligand family (TNFs) may induce both
apoptotic and anti-apoptotic pathways. TNFs transduces cellular responses through
activation of different TNF-receptors (TNFRs).
One important mechanism of cell survival is the activation of transcription of
different ...
Apoptosis and survival_Anti-apoptotic TNFs/NF-kB/IAP pathway [score: 1 (0%)]
Members of the tumour necrosis factor ligand family (TNFs) may induce both apoptotic
and anti-apoptotic pathways. TNFs transduces cellular responses through activation of
different TNF-receptors (TNFRs).
One important mechanism of cell survival is activation of transcription of different
anti-apoptotic ...
Apoptosis and survival_Lymphotoxin-beta receptor signaling [score: 1 (0%)]
Lymphotoxin-beta receptor (LTBR), a member of the tumor
necrosis factor receptor superfamily, is essential for the development and organization
of secondary lymphoid tissue. The LTBR binds specific
ligands, such as the membrane form of lymphotoxin heterotrimer, Lymphotoxin-Alpha1Beta2
(TNF-beta/LTB ...
Apoptosis and survival_APRIL and BAFF signaling [score: 1 (0%)]
Tumor necrosis factor (ligand) superfamily members 13 and 13b (APRIL
and BAFF) and their receptors - Tumor
necrosis factor receptor superfamily members 13C, 17 and 13B
(BAFF-R, BCMA and
TACI) - play important roles in the B-cell and T-cell arms
of the immune system ...
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