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DNA damage_ATM/ATR regulation of G1/S checkpoint [score: 1 (0%)]

ATM/ATR regulation of G1/S and S/G2 checkpoints

DNA damage checkpoints are biochemical pathways that delay or arrest the cell cycle progression in response to the DNA damage. All eukaryotic ...

Immune response_IL-4 signaling pathway [score: 1 (0%)]

IL-4 signaling pathway

Interleukin-4 (IL-4) is a T cell derived multifunctional cytokine that plays a critical role in the regulation of immune responses. IL-4 induces Th2 (T helper 2) differentiation, ...

Development_TGF-beta receptor signaling [score: 1 (0%)]

TGF-beta receptor signaling

Transforming growth factor beta (TGF-beta) signaling controls diverse cellular processes, including cell proliferation, differentiation, adhesion and migration [1], ...

Immune response_MIF in innate immunity response [score: 1 (0%)]

MIF in innate immunity response

The cytokine Macrophage migration inhibitory factor (MIF) is an integral mediator of the innate immune system. Monocytes, macrophages and lymphocytes constitutively ...

Immune response_MIF-JAB1 signaling [score: 1 (0%)]

MIF-JAB1 signaling

Macrophage migration inhibitory factor (MIF) is a pluripotent cytokine involved in inflammation and immune responses as well as in growth factor-dependent cell proliferation, cell ...

Development_VEGF signaling via VEGFR2 - generic cascades [score: 1 (0%)]

VEGF signaling via VEGFR2 - generic cascades

Abstract

VEGF family of ligands and receptors is crucial for vascular development and neovascularization in physiological and pathological ...

Development_VEGF signaling and activation [score: 1 (0%)]

VEGF signaling and activation

The vascular endothelial growth factor (VEGF) family of ligands and receptors is crucial for vascular development and neovascularization in physiological and pathological processes ...

Development_Prolactin receptor signaling [score: 1 (0%)]

Prolactin signaling

Prolactin is a polypeptide hormone secreted by the pituitary gland and to a lesser extent by numerous extrapituitary tissues. This hormone affects a great amount of physiological ...

Immune response_TLR2 and TLR4 signaling pathways [score: 1 (0%)]
TLR2 and TLR4 signaling pathways Abstract:

TLR2 and TLR4 induce MyD88/ IRAK/ TRAF6-dependent pathway in target cells, leading to activation of transcription factors NF-kB, ...

Apoptosis and survival_Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway [score: 1 (0%)]

Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway

The members of the tumour necrosis factor ligand family (TNFs) may induce both apoptotic and anti-apoptotic pathways. TNFs transduces cellular ...

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