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DNA damage_ATM/ATR regulation of G1/S checkpoint [score: 1 (0%)]
ATM/ATR regulation of G1/S and S/G2 checkpoints
DNA damage checkpoints are biochemical pathways that delay or arrest the
cell cycle progression in response to the DNA damage. All eukaryotic ...
Immune response_IL-4 signaling pathway [score: 1 (0%)]
IL-4 signaling pathway
Interleukin-4 (IL-4) is a T cell derived multifunctional cytokine
that plays a critical role in the regulation of immune responses. IL-4
induces Th2 (T helper 2) differentiation, ...
Development_TGF-beta receptor signaling [score: 1 (0%)]
TGF-beta receptor signaling
Transforming growth factor beta (TGF-beta) signaling controls
diverse cellular processes, including cell proliferation,
differentiation, adhesion and migration , ...
Immune response_MIF in innate immunity response [score: 1 (0%)]
MIF in innate immunity response
The cytokine Macrophage migration inhibitory factor (MIF) is an
integral mediator of the innate immune system. Monocytes, macrophages
and lymphocytes constitutively ...
Immune response_MIF-JAB1 signaling [score: 1 (0%)]
Macrophage migration inhibitory factor (MIF) is a pluripotent
cytokine involved in inflammation and immune responses as well as in
growth factor-dependent cell proliferation, cell ...
Development_VEGF signaling and activation [score: 1 (0%)]
VEGF signaling and activation
The vascular endothelial growth factor (VEGF) family of ligands and
receptors is crucial for vascular development and neovascularization in
physiological and pathological processes ...
Development_Prolactin receptor signaling [score: 1 (0%)]
Prolactin is a polypeptide hormone secreted by the pituitary
gland and to a lesser extent by numerous extrapituitary tissues. This
hormone affects a great amount of physiological ...
Immune response_TLR2 and TLR4 signaling pathways [score: 1 (0%)]
TLR2 and TLR4 signaling pathways
TLR2 and TLR4 induce MyD88/ IRAK/ TRAF6-dependent
pathway in target cells, leading to activation of transcription factors NF-kB, ...