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Transcription_CREB pathway [score: 1 (0%)]
CREB signaling pathway

Extracellular stimuli elicit changes in gene expression in target cells by activating intracellular protein kinase cascades that phosphorylate transcription factors within the nucleus. One of the best characterized stimulus-induced transcription factors ...

Transcription_Receptor-mediated HIF regulation [score: 1 (0%)]

Receptor-mediated HIF regulation

Insulin and Insulin-like growth factor 1 (IGF-1) induce Hypoxia-inducible factor 1 alpha subunit (HIF1A) [1], [2] ...

Immune response_IL-2 activation and signaling pathway [score: 1 (0%)]

IL-2 activation and signaling pathway

Interleukin-2 (IL-2) is a T-Cell-derived cytokine important in the regulation of growth and differentiation of T-Cells, B-Cells, natural killer cells, glioma cells, and cells of the monocyte lineage.

IL-2 signaling is mediated ...

Immune response_IL-4 signaling pathway [score: 1 (0%)]

IL-4 signaling pathway

Interleukin-4 (IL-4) is a T cell derived multifunctional cytokine that plays a critical role in the regulation of immune responses. IL-4 induces Th2 (T helper 2) differentiation, ...

Immune response _IFN gamma signaling pathway [score: 1 (0%)]

Interferon-gamma signaling

Interferons (IFNs) are pleiotropic cytokines that mediate anti-viral responses, inhibit proliferation and participate in immune surveillance and tumor suppression by inducing the ...

Development_Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis [score: 1 (0%)]

Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis

There are two families of transcription factors that play pivotal roles during mammalian skeletal muscle differentiation. ...

Development_EGFR signaling pathway [score: 1 (0%)]
EGFR signaling pathway

Epidermal growth factor receptor (EGFR) belongs to the ERBB family of receptor tyrosine kinases that contains four closely related members EGFR and ERBB2-4. They couple ...

Development_VEGF-family signaling [score: 1 (0%)]

VEGF-family signaling

The vascular endothelial growth factor (VEGF) family of ligands and receptors is crucial for vascular development and neovascularization in physiological and pathological processes ...

Cytoskeleton remodeling_FAK signaling [score: 1 (0%)]
FAK signaling

The biological importance of PTK2 protein tyrosine kinase 2, or Focal adhesion kinase 1 (FAK1)-mediated signal transduction is underscored by the fact that this tyrosine kinase plays a fundamental role in embryonic development, in control of cell migration, ...

G-protein signaling_G-Protein alpha-12 signaling pathway [score: 1 (0%)]

G-protein alpha-12 family signaling

Activation by ligands of G-protein coupled receptors that interact with the trimeric G-protein alpha-12/beta/gamma causes the exchange of GDP for GTP bound to G ...

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