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Transcription_CREB pathway [score: 1 (0%)]

Extracellular stimuli elicit changes in gene expression in target cells by activating intracellular protein kinase cascades that phosphorylate transcription factors within the nucleus. One of the best characterized stimulus-induced transcription factors is cyclic AMP (cAMP) responsive element binding ...

Transcription_Receptor-mediated HIF regulation [score: 1 (0%)]

Insulin and Insulin-like growth factor 1 (IGF-1) induce Hypoxia-inducible factor 1 alpha subunit (HIF1A) [1], [2] and HIF-induced Vascular endothelial growth factor (VEGF) expression [1], ...

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