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Protein Regulatory Pathways
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Transcription_CREB pathway [score: 1 (0%)]
CREB signaling pathway
Extracellular stimuli elicit changes in gene expression in target cells
by activating intracellular protein kinase cascades that phosphorylate
transcription factors within the nucleus. ...
Immune response _IFN gamma signaling pathway [score: 1 (0%)]
Interferon-gamma signaling
Interferons (IFNs) are pleiotropic cytokines that mediate anti-viral responses, inhibit proliferation and participate in immune surveillance and tumor suppression by inducing the transcription of a number of IFN-stimulated genes. The IFN family ...
Immune response_T cell receptor signaling pathway [score: 1 (0%)]
T cell receptor signaling pathway
T cell receptors (TCR) play a key role in functioning of T cells
and formation of the immunological synapse. It provides connection
between T cell and the antigen-presenting ...
Development_Angiotensin signaling via PYK2 [score: 1 (0%)]
Angiotensin activation of MAPKs via Pyk2
Angiotensin II, a major effector peptide of the
renin-angiotensin system, is believed to play a critical role in the pathogenesis of
cardiovascular remodeling associated with hypertension, heart failure, and
atherosclerosis. [1]
Angiotensin ...
Development_EGFR signaling pathway [score: 1 (0%)]
EGFR signaling pathway
Epidermal growth factor receptor (EGFR) belongs to the ERBB family of receptor tyrosine kinases that contains four closely related members EGFR and ERBB2-4. They couple the binding of the extracellular growth factor ligands to intracellular ...
Development_VEGF-family signaling [score: 1 (0%)]
VEGF-family signaling
The vascular endothelial growth factor (VEGF) family of ligands and receptors is
crucial for vascular development and neovascularization in physiological and pathological
processes in both embryos, and in adults [1].
VEGFs belong ...
Signal transduction_Erk Interactions: Inhibition of Erk [score: 1 (0%)]
Erk Interactions: Inhibition of Erk
Mitogen-activated protein kinase (MAPK) pathways regulate a variety of
physiological processes, such as cell growth, differentiation, and
apoptotic cell death. To date, ...
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