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Transcription_CREB pathway [score: 1 (0%)]
CREB signaling pathway
Extracellular stimuli elicit changes in gene expression in target cells
by activating intracellular protein kinase cascades that phosphorylate
transcription factors within the nucleus. ...
Immune response _IFN gamma signaling pathway [score: 1 (0%)]
Interferons (IFNs) are pleiotropic cytokines that mediate anti-viral
responses, inhibit proliferation and participate in immune surveillance
and tumor suppression by inducing the ...
Immune response_T cell receptor signaling pathway [score: 1 (0%)]
T cell receptor signaling pathway
T cell receptors
(TCR) play a key role in functioning of T cells
and formation of the immunological synapse. It provides connection
between T cell and the antigen-presenting ...
Development_Angiotensin signaling via PYK2 [score: 1 (0%)]
Angiotensin activation of MAPKs via Pyk2
Angiotensin II, a major effector peptide of the
renin-angiotensin system, is believed to play a critical role in the pathogenesis of
cardiovascular remodeling associated with hypertension, heart failure, and
atherosclerosis. [ 1] Angiotensin ...
Development_EGFR signaling pathway [score: 1 (0%)]
EGFR signaling pathway
Epidermal growth factor receptor (
EGFR) belongs to the ERBB
family of receptor tyrosine kinases that contains four closely related
members EGFR and ERBB2-4. They couple ...
Development_VEGF-family signaling [score: 1 (0%)]
The vascular endothelial growth factor (VEGF) family of ligands and
receptors is crucial for vascular development and neovascularization in
physiological and pathological processes ...
Signal transduction_Erk Interactions: Inhibition of Erk [score: 1 (0%)]
Erk Interactions: Inhibition of Erk
Mitogen-activated protein kinase (MAPK) pathways regulate a variety of
physiological processes, such as cell growth, differentiation, and
apoptotic cell death. To date, ...