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Androstenedione and testosterone biosynthesis and metabolism p.1 [score: 1 (0%)]
Androstenedione is a 19-carbon steroid hormone produced
as an intermediate step in the biochemical pathway that produces the androgen
Testosterone and the estrogens
Estrone and Estradiol.
Androstenedione originates either from the conversion of
Dehydroepiandrosterone ...
Estradiol metabolism [score: 1 (0%)]
Endogenous and exogenous estrogens undergo oxidative metabolism by hepatic microsomal
cytochrome P-450. Aromatic hydroxylation at either the C2 or C4 position is a major route
of Estradiol metabolism in humans and other mammals,
although there is less 4-hydroxylation than 2-hydroxylation. ...
Estrone metabolism [score: 1 (0%)]
Endogenous and exogenous estrogens undergo oxidative metabolism by hepatic microsomal
cytochrome P-450. Aromatic hydroxylation at either the C2 or C4 position is a major route
of Estrone metabolism in humans and other mammals, although
there are less 4-hydroxylation than 2-hydroxylation events. ...
Selected targets of Androgen and Estrogen receptors [score: 1 (0%)]
Androgen and Estrogen receptors (Androgen receptor and
ESR1 (nuclear)) function as steroid-hormone activated
transcription factors. Upon binding the hormone ligand, receptors dissociate from
accessory proteins, translocate into the nucleus, dimerize, and then stimulate
transcription ...
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