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Tyrosine metabolism p.1 (dopamine) [score: 1 (0%)]
(L)-Tyrosine is a non-essential
aminoacid that is synthesized in mammals from
(L)-Phenylalanine by Phenylalanine hydroxylase
(PAH) [1].
(L)-Tyrosine, as other proteogenic aminoacids, conjugates
with corresponding tRNA forming ...
Androstenedione and testosterone biosynthesis and metabolism p.1 [score: 1 (0%)]
Androstenedione is a 19-carbon steroid hormone produced
as an intermediate step in the biochemical pathway that produces the androgen
Testosterone and the estrogens
Estrone and Estradiol.
Androstenedione originates either from the conversion of
Dehydroepiandrosterone ...
Estradiol metabolism [score: 1 (0%)]
Endogenous and exogenous estrogens undergo oxidative metabolism by hepatic microsomal
cytochrome P-450. Aromatic hydroxylation at either the C2 or C4 position is a major route
of Estradiol metabolism in humans and other mammals,
although there is less 4-hydroxylation than 2-hydroxylation. ...
Estrone metabolism [score: 1 (0%)]
Endogenous and exogenous estrogens undergo oxidative metabolism by hepatic microsomal
cytochrome P-450. Aromatic hydroxylation at either the C2 or C4 position is a major route
of Estrone metabolism in humans and other mammals, although
there are less 4-hydroxylation than 2-hydroxylation events. ...
Glutathione metabolism [score: 1 (0%)]
Glutathione can be found in the cell in oxidized (Glutathione
disulfide) and reduced (Glutathione) form.
Reduced glutathione can be either directly formed from Glutathione
disulfide as the result of activity of Glutathione reductase
(GSHR) [1], ...
Glycolysis and gluconeogenesis (short map) [score: 1 (0%)]
D-Glucose is the major energy source for mammalian cells
as well as an important substrate for protein and lipid synthesis. Mammalian cells take
up D-Glucose from extracellular fluid into the cell through
two families of structurally related glucose transporters. Solute carrier family ...
2-Naphthylamine and 2-Nitronaphtalene metabolism [score: 1 (0%)]
Metabolism and binding studies with 2-Naphthylamine and
many other arylamines have shown cytochrome P-450 catalysed N-hydroxylation to be a
critical step in the activation of these compounds. Followed by glucuronidation and
excretion of the glucuronides via the kidney, this reaction can account ...
Naphthalene metabolism [score: 1 (0%)]
Toxicity of Naphthalene in cell culture and animal models
has to do with metabolisation of this compound by cytochrome P450 monooxygenases.
Deactivation of Naphthalene involves epoxidation followed by
glutathione conjugation and mercapturic acid formation [1].
Naphthalene ...
Lipase family functions [score: 1 (0%)]
Lipases are water-soluble enzymes that catalyze the hydrolysis of ester chemical bonds
in water-insoluble lipid substrates. Lipases are widely distributed in animals, plants
and prokaryotes. The lipase family consists of triglyceride lipases, phospholipases and
sphingomyelinases. By the place of ...
Fructose metabolism [score: 1 (0%)]
D-Sucrose and Glycogen are
the primary sources of D-fructose synthesis.
D-Sucrose is hydrolyzed to
D-fructose and D-Glucose by
Maltase-glucoamylase (MGAM) and Sucrase-isomaltase
(SUIS) [1]. Ketohexokinase
(KHK) ...
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