The cytokine Macrophage migration inhibitory factor (MIF) is an integral mediator of the innate immune system. Monocytes, macrophages and lymphocytes constitutively express MIF, which is rapidly released after exposure to bacterial toxins and cytokines. MIF exerts potent proinflammatory ...

CCAAT/enhancer binding proteins (C/EBP) are a group of bZIP transcription factors, consisting of C/EBPalpha, beta, delta, epsilon, gamma and zeta, which can bind as homodimers to certain promoters and enhancers. C/EBP is important in the regulation ...