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Regulatory Processes
Diseases
Protein Regulatory Pathways
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Translation _Regulation of EIF4F activity [score: 1 (0%)]
Protein biosynthesis is largely governed by a cohort of Eukaryotic translation
initiation factors (eIF) that mediate specific steps in the
initiation process. A rate-limiting step in translation
initiation involves formation of the eIF4F complex that
recruits ...
Translation _Regulation of EIF2 activity [score: 1 (0%)]
Eukaryotic translation initiation factors (eIF2) is a
G-protein that is composed of 3 non-identical subunits,
eIF2S1, eIF2S2
and eIF2S3, and catalyzes the first regulated
step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S
ribosomal ...
Signal transduction_PTEN pathway [score: 1 (0%)]
Phosphatase and tensin homolog (PTEN) is a known tumor
suppressor. It inhibits growth factor-induced cell proliferation, division and regulates
Integrin-mediated cell adhesion and survival [1].
PTEN antagonizes Phosphoinositide-3-kinase
(PI3K), ...
Translation_Insulin regulation of translation [score: 1 (0%)]
Insulin plays an important role in the overall regulation
of protein synthesis. Protein synthesis (mRNA translation) is conventionally divided into
three stages: initiation, elongation and termination. Both initiation and elongation can
be controlled by Insulin.
Insulin ...
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