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Translation_Regulation of EIF4F activity [score: 1 (0%)]
Regulation of eIF4 activity
Protein biosynthesis is largely governed by a cohort of Eukaryotic translation
initiation factors (
eIF) that mediate specific steps in the
initiation process . A rate-limiting step in translation
initiation involves formation ...
Translation _Regulation of EIF2 activity [score: 1 (0%)]
Regulation of eIF2 activity
Eukaryotic translation initiation factors (
eIF2) is a G-protein
that is composed of 3 non-identical subunits, eIF2S1, eIF2S2 and
eIF2S3, and catalyzes ...
Signal transduction_AKT signaling [score: 1 (0%)]
RAC-alpha serine/threonine kinases (
AKTs) are crucial mediators
of various cellular process, such as apoptosis, regulation of cell
cycle, protein synthesis and regulation of metabolism. The ...
Signal transduction_PTEN pathway [score: 1 (0%)]
Phosphatase and tensin homolog (
PTEN) is a known tumor
suppressor. It inhibits growth factor-induced cell proliferation,
division and regulates Integrin-mediated cell adhesion ...
Translation_Insulin regulation of translation [score: 1 (0%)]
Insulin regulation of translation.
Insulin plays an important role in the overall regulation of
protein synthesis. Protein synthesis (mRNA translation) is
conventionally divided into three stages: ...
Selected targets of SP1 [score: 1 (0%)]
Selected targets of SP1
Sp1 transcription factor (
SP1) is a transcription factor involved in gene expression in the early development of an organism. It belongs to the Sp/KLF family of transcription factors. The SP1 transcription factor contains a zinc ...
Selected targets of HNF transcription factors [score: 1 (0%)]
Selected targets of HNF transcription factors
Hepatocyte nuclear factors (HNFs) are a group of phylogenetically
unrelated transcription factors that regulate the transcription of a
diverse group of genes. ...