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Immune response_MIF in innate immunity response [score: 1 (0%)]
The cytokine Macrophage migration inhibitory factor (MIF)
is an integral mediator of the innate immune system. Monocytes, macrophages and
lymphocytes constitutively express MIF, which is rapidly
released after exposure to bacterial toxins and cytokines.
MIF exerts potent proinflammatory ...
Immune response_TLR signaling pathways [score: 1 (0%)]
Both gram-positive and gram-negative bacteria and their cell wall components activate
innate immune system of the host and induce secretion of proinflammatory molecules,
mainly chemokines and cytokines [1]. Toll-like receptors (TLRs) initiate
signaling cascades through ...
Apoptosis and survival_Lymphotoxin-beta receptor signaling [score: 1 (0%)]
Lymphotoxin-beta receptor (LTBR), a member of the tumor
necrosis factor receptor superfamily, is essential for the development and organization
of secondary lymphoid tissue. The LTBR binds specific
ligands, such as the membrane form of lymphotoxin heterotrimer, Lymphotoxin-Alpha1Beta2
(TNF-beta/LTB ...
Cytokine production by Th17 cells in CF [score: 1 (0%)]
Cystic Fibrosis (CF) is a potentially lethal genetic disease that typically results in
the development of bronchial inflammation, bronchiectasis, the progressive loss of lung
function and, ultimately, death [1].
CF is caused by genetic defects in Cystic Fibrosis ...
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