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Regulatory Processes
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Protein Regulatory Pathways
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Immune response_Alternative complement pathway [score: 1 (0%)]
Complement system is a major effector of humoral branch of the immune system, acting
to protect the host from microorganisms, such as bacteria.
Complement components are designated either by numerals
(C1-C9), letter symbols (e.g.,
Complement factor I (Factor I)), or by ...
Immune response_IL-6 signaling pathway [score: 1 (0%)]
Interleukin-6 (IL-6) is a pleiotropic cytokine produced
by various types of lymphoid and nonlymphoid cells, such as T cells, B cells, monocytes,
fibroblasts, keratinocytes, endothelial cells, mesangial cells and several tumor cells.
IL-6 provokes a broad range of cellular and physiological
responses, ...
Immune response_MIF in innate immunity response [score: 1 (0%)]
The cytokine Macrophage migration inhibitory factor (MIF)
is an integral mediator of the innate immune system. Monocytes, macrophages and
lymphocytes constitutively express MIF, which is rapidly
released after exposure to bacterial toxins and cytokines.
MIF exerts potent proinflammatory ...
Immune response_TLR signaling pathways [score: 1 (0%)]
Both gram-positive and gram-negative bacteria and their cell wall components activate
innate immune system of the host and induce secretion of proinflammatory molecules,
mainly chemokines and cytokines [1]. Toll-like receptors (TLRs) initiate
signaling cascades through ...
Immune response_IL-1 signaling pathway [score: 1 (0%)]
Interleukin-1 (IL-1) is a proinflammatory cytokine produced by activated macrophages,
endothelial cells, B cells and fibroblasts. IL-1 stimulates a broad spectrum of immune
and inflammatory responses [1], [2].
There are two forms of ...
Immune response_MIF-mediated glucocorticoid regulation [score: 1 (0%)]
Glucocorticoids are potent anti-inflammatory and
immunosuppressive agents. They inhibit synthesis of almost all known cytokines, enzymes
involved in the inflammatory process and several cell surface molecules required for
immune function. Glucocorticoids mediate these effects via
the ...
Classical complement pathway [score: 1 (0%)]
Complement system is a major effector of the humoral branch of the immune system,
acting to protect the host from microorganisms such as bacteria.
Complement components are designated by numerals (C1-C9), by letter symbols (e.g.,
Complement factor I (Factor I)), or by other trivial ...
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