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Immune response_MIF-JAB1 signaling [score: 1 (0%)]

Macrophage migration inhibitory factor (MIF) is a pluripotent cytokine involved in inflammation and immune responses as well as in growth factor-dependent cell proliferation, cell cycle, angiogenesis, and tumorigenesis [1], [2], [3], ...

Transcription_Ligand-dependent activation of the ESR1/SP pathway [score: 1 (0%)]

Estrogen receptor 1 (ESR1) is a major ligand-activated transcription factor, member of the family nuclear receptors [1]. ESR1 acts via two main pathways: a ligand-dependent and ligand-independent manner [2]. Activated by a ligand, ESR1 ...

Selected targets of SP1 [score: 1 (0%)]

Sp1 transcription factor (SP1) is a transcription factor involved in gene expression in the early development of an organism. It belongs to the Sp/KLF family of transcription factors. The SP1 transcription factor contains a zinc finger protein motif, by which it binds directly to DNA ...

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