Antigen processing and presentation is the process by which antigen-presenting cells express antigen on their cell surface in a form recognizable by lymphocytes.

Oncostatin M is a multifunctional cytokine produced by activated T lymphocytes, monocytes and microglia. It is structurally and functionally related to the subfamily of hematopoietic and neurotrophic cytokines known as the Interleukin 6 (IL6)-type cytokine family [1].

Oncostatin M is a multifunctional cytokine produced by activated T lymphocytes, monocytes, microglia. It is structurally and functionally related to the subfamily of hematopoietic and neurotrophic cytokines known as the Interleukin 6 (IL6)-type cytokine family [1].

Prostaglandin E2 (PGE2) is a crucial mediator of inflammatory pain sensitization. Prostaglandin E2 is produced in response to inflammation both in peripheral inflamed tissues and in the spinal cord [1].

Cystic Fibrosis (CF) is a potentially lethal genetic disease that typically results in the development of bronchial inflammation, bronchiectasis, the progressive loss of lung function and, ultimately, death [1].

The upper airways represent a primary site for the introduction of pathogenic microorganisms from inspired air. The ciliated epithelium features several powerful mechanisms for prevention of colonization by inhaled bacteria, thus the lower respiratory tract usually remains sterile [1].