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DNA damage_ATM/ATR regulation of G1/S checkpoint [score: 1 (0%)]

DNA damage checkpoints are biochemical pathways that delay or arrest the cell cycle progression in response to the DNA damage. All eukaryotic cells have four phases within the cell cycle, G1, S, G2, and M, and one outside, G0 [1].

The G1/S checkpoint prevents cells ...

DNA damage_Role of Brca1 and Brca2 in DNA repair [score: 1 (0%)]

DNA damage-dependent activation of the breast and ovarian cancer susceptibility protein 1 (Brca1) occurs via activation of ataxia telangiectasia mutated serine-protein kinase (ATM) [1] or ataxia telangiectasia and Rad3 related protein kinase (ATR) ...

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