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Apoptosis and survival_Regulation of Apoptosis by Mitochondrial Proteins [score: 1 (0%)]

Regulation of Apoptosis by Mitochondrial Proteins

Apoptosis is an evolutionarily conserved type of programmed cell death essential for development, homeostasis, and self-defense against infection. It can ...

Apoptosis and survival_Caspase cascade [score: 1 (0%)]

Caspase cascade

Caspases are the central components of the apoptotic response. The apoptotic caspases are generally divided into two classes: the initiator caspases, which include ...

Transcription_P53 signaling pathway [score: 1 (0%)]

p53 signaling pathway

The Tumor protein p53 (p53) plays a critical role in safeguarding the integrity of the genome. Upon activation, p53 binds to the enhancer/promoter elements of downstream ...

DNA damage_ATM/ATR regulation of G1/S checkpoint [score: 1 (0%)]

ATM/ATR regulation of G1/S and S/G2 checkpoints

DNA damage checkpoints are biochemical pathways that delay or arrest the cell cycle progression in response to the DNA damage. All eukaryotic ...

DNA damage_Role of Brca1 and Brca2 in DNA repair [score: 1 (0%)]

Role of Brca1 and Brca2 in DNA Repair

DNA damage-dependent activation of the breast and ovarian cancer susceptibility protein 1 (Brca1) occurs via activation of ataxia telangiectasia mutated serine-protein ...

Apoptosis and survival_BAD phosphorylation [score: 1 (0%)]

BAD phosphorylation

BAD is a member of the BCL-2 family. BCL-2 family members are regulators of the programmed cell death pathways.

BAD induces apoptosis by inhibiting antiapoptotic ...

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