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Development_Angiotensin signaling via PYK2 [score: 1 (0%)]

Angiotensin II, a major effector peptide of the renin-angiotensin system, is believed to play a critical role in the pathogenesis of cardiovascular remodeling associated with hypertension, heart failure, and atherosclerosis. [1]

Angiotensin II receptor, ...

Development_VEGF signaling via VEGFR2 - generic cascades [score: 1 (0%)]

VEGF family of ligands and receptors is crucial for vascular development and neovascularization in physiological and pathological processes in both embryo and adult. VEGFR-2 is a high-affinity receptor for VEGF-A. Activated VEGFR-2 can activate p38 MAPK, PI3K reg class IA/ ...

Development_VEGF signaling and activation [score: 1 (0%)]

The vascular endothelial growth factor (VEGF) family of ligands and receptors is crucial for vascular development and neovascularization in physiological and pathological processes in both embryo and adult [1]. VEGFs denote a family of homodimeric glycoproteins that currently ...

Development_Angiotensin signaling via beta-Arrestin [score: 1 (0%)]

Angiotensin II, a major effector peptide of the renin-angiotensin system, is now believed to play a critical role in the pathogenesis of cardiovascular remodeling associated with hypertension, heart failure, and atherosclerosis [1].

Angiotensin II receptor ...

Development_EDNRB signaling [score: 1 (0%)]

Endothelin receptor type B (EDNRB) belongs to the guanine nucleotide binding protein (G-protein) coupled receptor family. Endothelin-1 is most investigated physiological ligand of EDNRB [1]. EDNRB binds to many types of the G-proteins but the ...

Selected targets of SP1 [score: 1 (0%)]

Sp1 transcription factor (SP1) is a transcription factor involved in gene expression in the early development of an organism. It belongs to the Sp/KLF family of transcription factors. The SP1 transcription factor contains a zinc finger protein motif, by which it binds directly to DNA ...

Angiotensin activation of ERK [score: 1 (0%)]

Angiotensin II, a major effector peptide of the renin-angiotensin system, and is believed to play a critical role in the pathogenesis of cardiovascular remodeling associated with hypertension, heart failure, and atherosclerosis [1]. Angiotensin II acts via Angiotensin ...

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