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Transcription_NF-kB activation pathways [score: 1 (0%)]
NF-kB activation pathways Abstract:

Pathways of NF-kB activation in response to different stimuli are broadly classified as the canonical and non-canonical pathways, depending on whether activation involves I-kB degradation or NF-kB2 (p100) processing. ...

Apoptosis and survival_TNFR1 signaling pathway [score: 1 (0%)]
Role TNF-alpha in apoptosis

The tumor necrosis factor (TNF-alpha) is a potent cytokine produced by many cell types, including macrophages, monocytes, lymphocytes, keratinocytes and fibroblasts, in response ...

Immune response_Alternative complement pathway [score: 1 (0%)]

Alternative complement pathway

Complement system is a major effector of humoral branch of the immune system, acting to protect the host from microorganisms, such as bacteria.

Complement components ...

Immune response_IL-6 signaling pathway [score: 1 (0%)]

IL-6 signaling pathway

Interleukin-6 (IL-6) is a pleiotropic cytokine produced by various types of lymphoid and nonlymphoid cells, such as T cells, B cells, monocytes, fibroblasts, keratinocytes, ...

Immune response_MIF in innate immunity response [score: 1 (0%)]

MIF in innate immunity response

The cytokine Macrophage migration inhibitory factor (MIF) is an integral mediator of the innate immune system. Monocytes, macrophages and lymphocytes constitutively ...

Signal transduction_JNK pathway [score: 1 (0%)]

JNK pathway

The Mitogen-activated protein kinases 8-10 (JNK(MAPK8-10)) belong to a sub-group of evolutionarily conserved mitogen-activated protein kinases (MAPK) activated primarily by cytokines, growth factors and by exposure to environmental stress. JNK(MAPK8-10) activity ...

Transcription_PPAR Pathway [score: 1 (0%)]

PPAR Pathway

Peroxisome Proliferator-Activated Receptors (PPAR) are ligand-inducible transcription factors that belong to the nuclear hormone receptor superfamily. The PPAR group consists of ...

Immune response_TLR2 and TLR4 signaling pathways [score: 1 (0%)]
TLR2 and TLR4 signaling pathways Abstract:

TLR2 and TLR4 induce MyD88/ IRAK/ TRAF6-dependent pathway in target cells, leading to activation of transcription factors NF-kB, ...

Immune response_IL-1 signaling pathway [score: 1 (0%)]

IL-1 signaling pathway

Interleukin-1 (IL-1) is a proinflammatory cytokine produced by activated macrophages, endothelial cells, B cells and fibroblasts. IL-1 stimulates a broad spectrum of immune and inflammatory ...

Immune response_Lectin induced complement pathway [score: 1 (0%)]

Lectin induced complement pathway

The complement system is the major effector of the humoral branch of the immune system, acting to protect the host from microorganisms such as bacteria.

...

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