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Development_A2B receptor: action via G-protein alpha s [score: 1 (0%)]
Adenosine A2B
receptor influences cell differentiation and proliferation.
A2B receptors are G-protein-coupled receptors coupling to
classical second messenger pathways, such as modulation of Cyclic Adenosine
3',5'-phosphate (cAMP)
production or the Phospholipase ...
Development_Prolactin receptor signaling [score: 1 (0%)]
Prolactin is a polypeptide hormone secreted by the
pituitary gland and to a lesser extent by numerous extrapituitary tissues. This hormone
affects a great amount of physiological processes [1]. Numerous biological
functions have been attributed to this hormone's ...
Development_Endothelin-1/EDNRA transactivation of EGFR [score: 1 (0%)]
Endothelin-1, a potent endothelium-derived
vasoconstrictor peptide, exerts a growth-promoting effect on vascular smooth muscle
cells, implicating its pathogenic role in vascular remodeling.
Endothelin-1 action is initiated by its binding to
Endothelin receptor type A (EDNRA) ...
Development_Endothelin-1/EDNRA signaling [score: 1 (0%)]
Endothelin-1, a potent endothelium-derived
vasoconstrictor peptide, exerts a growth-promoting effect on vascular smooth muscle
cells, implicating its pathogenic role in vascular remodeling.
Endothelin-1 action is exerted by its binding to Endothelin
receptor type A (EDNRA) [
Development_EDNRB signaling [score: 1 (0%)]
Endothelin receptor type B (EDNRB) belongs to the guanine
nucleotide binding protein (G-protein) coupled receptor family.
Endothelin-1 is most investigated physiological ligand of
EDNRB [1]. EDNRB
binds to many types of the G-proteins but the ...
Development_Activation of ERK by Alpha-1 adrenergic receptors [score: 1 (0%)]
Subtype alpha-1 adrenergic receptors consists of Alpha-1A adrenergic
receptor, Alpha-1B adrenergic receptor and
Alpha-1D adrenergic receptor. They participate in many
physiological processes via different pathways. One of the best studied alpha-1
adrenergic receptors-stimulated ...
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