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Development_Ligand-independent activation of ESR1 and ESR2 [score: 1 (0%)]

In addition to the conventional hormone-dependent regulation of activity of Estrogen receptor alpha and beta (ESR1(nuclear) and ESR2 respectively), there is a cross-talk between signal transduction pathways and estrogen receptors [1]. Epidermal growth factor (EGF), ...

Cell cycle_ESR1 regulation of G1/S transition [score: 1 (0%)]

Estradiol induces proliferation of estrogen receptor-positive cells. ESR1 (nuclear) activated by Estradiol acts like as ligand-dependent ...

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