The biological importance of PTK2 protein tyrosine kinase 2, or Focal
adhesion kinase 1 (FAK1)-mediated signal transduction is
underscored by the fact that this tyrosine kinase plays a fundamental role in embryonic
development, in control of cell migration, cell ...
The family of Protein kinase C (PKC)
contains 3 functional protein types, "conventional"
PKC-alpha, PKC-beta, and
PKC-gamma that are activated by calcium and Diacylglycerol
(DAG), "novel" PKC-delta,
PKC-epsilon, PKC-eta, ...
Notch homolog 1 translocation-associated (NOTCH1) is
synthesized as NOTCH1 precursor, which is cleaved by
Furin to NOTCH1receptor form. NOTCH1 receptor
is activated by Jagged . O-fucosylpeptide
Hepatocyte growth factor/Scatter factor (HGF) is a
multifunctional growth factor which induces cell dissociation, migration, protection from
apoptosis, proliferation and differentiation . Receptor Met
proto-oncogene (HGF receptor ...