Results

There are two families of transcription factors that play pivotal roles during mammalian skeletal muscle differentiation. One of them includes MyoD family proteins (also called myogenic regulatory ...

Development_FGFR signaling pathway [score: 1 (0%)]

FGFR signaling pathway

Fibroblast growth factor 2 (FGF2) has been implicated in diverse cellular processes, including apoptosis, cell survival, chemotaxis, cell adhesion, migration, differentiation, and proliferation [1].

FGF2 induces ...

Cytoskeleton remodeling_FAK signaling [score: 1 (0%)]

FAK signaling

The biological importance of PTK2 protein tyrosine kinase 2, or Focal adhesion kinase 1 (FAK1)-mediated signal transduction is underscored by the fact that this tyrosine kinase plays a fundamental role in embryonic development, in control of cell migration, cell ...

Signal transduction_Activation of PKC via G-Protein coupled receptor [score: 1 (0%)]

PKC family signaling

The family of Protein kinase C (PKC) contains 3 functional protein types, "conventional" PKC-alpha, PKC-beta, and PKC-gamma that are activated by calcium and Diacylglycerol (DAG), "novel" PKC-delta, PKC-epsilon, PKC-eta, ...

Development_G-Proteins mediated regulation MAPK-ERK signaling [score: 1 (0%)]

G-protein-mediated regulation of MAPK-ERK signaling

Guanine nucleotide binding protein (G-proteins) are heterotrimeric signaling molecules composed of three subunits, alpha, beta, and gamma, which ...

Development_TGF-beta receptor signaling [score: 1 (0%)]

TGF-beta receptor signaling

Transforming growth factor beta (TGF-beta) signaling controls diverse cellular processes, including cell proliferation, differentiation, adhesion and migration [1], [2], [3].

TGF-beta ...

Development_A2B receptor: action via G-protein alpha s [score: 1 (0%)]

Adenosine A2B receptor signaling

Adenosine A2B receptor influences cell differentiation and proliferation. A2B receptors are G-protein-coupled receptors coupling to classical second ...

Development_Notch Signaling Pathway [score: 1 (0%)]

Notch Signaling Pathway

Notch homolog 1 translocation-associated (NOTCH1) is synthesized as NOTCH1 precursor, which is cleaved by Furin to NOTCH1 receptor form. NOTCH1 receptor is activated by Jagged [1]. O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase ...

Development_NOTCH1-mediated pathway for NF-KB activity modulation [score: 1 (0%)]

NOTCH1-mediated pathway for NF-KB activity modulation

Interleukin 1 (IL-1) activates Nuclear factor of kappa light polypeptide gene enhancer in B-cells (NF-KB) via Interleukin-1 receptor-associated kinase (IRAK) and Mitogen-activated protein kinase kinase kinase ...

Development_HGF signaling pathway [score: 1 (0%)]

HGF signaling

Hepatocyte growth factor/Scatter factor (HGF) is a multifunctional growth factor which induces cell dissociation, migration, protection from apoptosis, proliferation and differentiation [1]. Receptor Met proto-oncogene (HGF receptor ...

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