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Protein Regulatory Pathways
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| Showing 31 - 39 out of 39 |
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Lipase family functions [score: 1 (0%)]
Lipases are water-soluble enzymes that catalyze the hydrolysis of ester chemical bonds
in water-insoluble lipid substrates. Lipases are widely distributed in animals, plants
and prokaryotes. The lipase family consists of triglyceride lipases, phospholipases and
sphingomyelinases. By the place of ...
Regulation of keratinocyte and melanocyte differentiation [score: 1 (0%)]
Keratinocytes and melanocytes are prevalent cell types of the epidermal layer of the
skin. Melanocytes are responsible for producing melanin. This process is known as
melanogenesis.
Pigmentation in mammals is stimulated mainly by Alpha-melanocyte stimulating hormone
(alpha-MSH) and ...
Manganese, Calcium and Iron-regulated proteins [score: 1 (0%)]
Proteins, regulated by binding of inorganic ions, are very important for different
aspects of cell functioning.
There is a wide variety of Calcium, Manganese and Iron-regulated proteins inside and
out of the cells.
Binding of Ca('2+) extracellular region to receptors of
L-Glutamic ...
Selected targets of Androgen and Estrogen receptors [score: 1 (0%)]
Androgen and Estrogen receptors (Androgen receptor and
ESR1 (nuclear)) function as steroid-hormone activated
transcription factors. Upon binding the hormone ligand, receptors dissociate from
accessory proteins, translocate into the nucleus, dimerize, and then stimulate
transcription ...
Selected targets of SP1 [score: 1 (0%)]
Sp1 transcription factor (SP1) is a transcription factor
involved in gene expression in the early development of an organism. It belongs to the
Sp/KLF family of transcription factors. The SP1
transcription factor contains a zinc finger protein motif, by which it binds directly to
DNA ...
Selected targets of c-Myc [score: 1 (0%)]
V-myc myelocytomatosis viral oncogene homolog (c-Myc) is
a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression,
apoptosis and cellular transformation. c-Myc controls the
transcription of a variety of different targets and regulates different processes, ...
Selected targets of EGR1 [score: 1 (0%)]
Early growth response 1 (EGR1) and Early growth response
2 (EGR2 (Krox20)) belong to the EGR family of C2H2-type
zinc-finger proteins, which function as a transcriptional regulators.
EGR1 activates a wide variety of different targets, which
are required for cell proliferation, ...
Selected targets of C/EBP [score: 1 (0%)]
CCAAT/enhancer binding proteins (C/EBP) are a group of
bZIP transcription factors, consisting of C/EBPalpha,
beta, delta,
epsilon, gamma and
zeta, which can bind as homodimers to certain promoters and
enhancers. C/EBP is important in the regulation ...
Selected targets of CREB1 [score: 1 (0%)]
cAMP responsive element binding protein 1 (CREB1) is a
transcription factor that is a member of the leucine zipper family of DNA binding
proteins. CREB1 binds as a homodimer to the cAMP-responsive
element, an octameric palindrome. CREB1 is phosphorylated by
several protein kinases, ...
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