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Development_Angiotensin signaling via PYK2 [score: 1 (0%)]

Angiotensin II, a major effector peptide of the renin-angiotensin system, is believed to play a critical role in the pathogenesis of cardiovascular remodeling associated with hypertension, heart failure, and atherosclerosis. [1]

Angiotensin II receptor, ...

Development_TGF-beta receptor signaling [score: 1 (0%)]

Transforming growth factor beta (TGF-beta) signaling controls diverse cellular processes, including cell proliferation, differentiation, adhesion and migration [1], [2], [3].

TGF-beta 1 initiates ...

Development_Notch Signaling Pathway [score: 1 (0%)]

Notch homolog 1 translocation-associated (NOTCH1) is synthesized as NOTCH1 precursor, which is cleaved by Furin to NOTCH1 receptor form. NOTCH1 receptor is activated by Jagged [1]. O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase ...

Development_NOTCH1-mediated pathway for NF-KB activity modulation [score: 1 (0%)]

Interleukin 1 (IL-1) activates Nuclear factor of kappa light polypeptide gene enhancer in B-cells (NF-KB) via Interleukin-1 receptor-associated kinase (IRAK) and Mitogen-activated protein kinase kinase kinase 1 (MEKK1(MAP3K1))-dependent inhibition of nuclear factor of kappa ...

Development_Prolactin receptor signaling [score: 1 (0%)]

Prolactin is a polypeptide hormone secreted by the pituitary gland and to a lesser extent by numerous extrapituitary tissues. This hormone affects a great amount of physiological processes [1]. Numerous biological functions have been attributed to this hormone's ...

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