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Transcription_Ligand-Dependent Transcription of Retinoid-Target genes [score: 1 (0%)]
Ligand Dependent Transcription of Retinoid-Target
genes
Retinoid receptors are asymmetrically oriented Retinoic acid receptor (RAR)/ Retinoid
X receptor (RXR) heterodimers that bind to specific DNA sequences or Retinoic acid
response elements (RAREs) in the promoters ...
Development_Angiotensin signaling via PYK2 [score: 1 (0%)]
Angiotensin activation of MAPKs via Pyk2
Angiotensin II, a major effector peptide of the
renin-angiotensin system, is believed to play a critical role in the pathogenesis of
cardiovascular remodeling associated with hypertension, heart failure, and
atherosclerosis. [1]
Angiotensin ...
Development_TGF-beta receptor signaling [score: 1 (0%)]
TGF-beta receptor signaling
Transforming growth factor beta (TGF-beta) signaling
controls diverse cellular processes, including cell proliferation, differentiation,
adhesion and migration [1], [2], [3].
TGF-beta ...
Development_Notch Signaling Pathway [score: 1 (0%)]
Notch Signaling Pathway
Notch homolog 1 translocation-associated (NOTCH1) is
synthesized as NOTCH1 precursor, which is cleaved by
Furin to NOTCH1
receptor form. NOTCH1 receptor
is activated by Jagged [1]. O-fucosylpeptide
3-beta-N-acetylglucosaminyltransferase ...
Development_NOTCH1-mediated pathway for NF-KB activity modulation [score: 1 (0%)]
NOTCH1-mediated pathway for NF-KB activity
modulation
Interleukin 1 (IL-1) activates Nuclear factor of kappa
light polypeptide gene enhancer in B-cells (NF-KB) via
Interleukin-1 receptor-associated kinase (IRAK) and
Mitogen-activated protein kinase kinase kinase ...
Cytoskeleton remodeling_Reverse signaling by ephrin B [score: 1 (0%)]
Reverse signaling by Ephrin B
Ephrin receptors and Ephrins
are both membrane bound, and following their interaction and clustering, each can
transduce signals that regulate cell responses [1].
Ephrin receptors activate reverse ...
Development_Prolactin receptor signaling [score: 1 (0%)]
Prolactin signaling
Prolactin is a polypeptide hormone secreted by the
pituitary gland and to a lesser extent by numerous extrapituitary tissues. This hormone
affects a great amount of physiological processes [1]. Numerous biological
functions have ...
Development_Angiotensin signaling via beta-Arrestin [score: 1 (0%)]
Angiotensin signaling via Beta-arrestin
Angiotensin II, a major effector peptide of the
renin-angiotensin system, is now believed to play a critical role in the pathogenesis of
cardiovascular remodeling associated with hypertension, heart failure, and
atherosclerosis [1].
Angiotensin ...
Development_Neurotrophin family signaling [score: 1 (0%)]
Neurotrophin family signaling
Factors of the neurotrophin family (NGF,
BDNF and neurotrophins NT-3 and
NT-4/5), promote neuronal survival or death. The best
characterized receptors for these trophic factors are the tropomyosin-related tyrosine
kinase receptors ...
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