Results

Retinoid receptors are asymmetrically oriented Retinoic acid receptor (RAR)/ Retinoid X receptor (RXR) heterodimers that bind to specific DNA sequences or Retinoic acid response elements (RAREs) in the promoters of a large number of retinoid-target genes [1], [2], ...

Development_Angiotensin signaling via PYK2 [score: 1 (0%)]

Angiotensin II, a major effector peptide of the renin-angiotensin system, is believed to play a critical role in the pathogenesis of cardiovascular remodeling associated with hypertension, heart failure, and atherosclerosis. [1]

Angiotensin II receptor, ...

Development_TGF-beta receptor signaling [score: 1 (0%)]

Transforming growth factor beta (TGF-beta) signaling controls diverse cellular processes, including cell proliferation, differentiation, adhesion and migration [1], [2], [3].

TGF-beta 1 initiates ...

Development_Notch Signaling Pathway [score: 1 (0%)]

Notch homolog 1 translocation-associated (NOTCH1) is synthesized as NOTCH1 precursor, which is cleaved by Furin to NOTCH1 receptor form. NOTCH1 receptor is activated by Jagged [1]. O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase ...

Development_NOTCH1-mediated pathway for NF-KB activity modulation [score: 1 (0%)]

Interleukin 1 (IL-1) activates Nuclear factor of kappa light polypeptide gene enhancer in B-cells (NF-KB) via Interleukin-1 receptor-associated kinase (IRAK) and Mitogen-activated protein kinase kinase kinase 1 (MEKK1(MAP3K1))-dependent inhibition of nuclear factor of kappa ...

Cytoskeleton remodeling_Reverse signaling by ephrin B [score: 1 (0%)]

Ephrin receptors and Ephrins are both membrane bound, and following their interaction and clustering, each can transduce signals that regulate cell responses [1].

Ephrin receptors activate reverse signaling through their Ephrin ligands ...

Development_Prolactin receptor signaling [score: 1 (0%)]

Prolactin is a polypeptide hormone secreted by the pituitary gland and to a lesser extent by numerous extrapituitary tissues. This hormone affects a great amount of physiological processes [1]. Numerous biological functions have been attributed to this hormone's ...

Development_Angiotensin signaling via beta-Arrestin [score: 1 (0%)]

Angiotensin II, a major effector peptide of the renin-angiotensin system, is now believed to play a critical role in the pathogenesis of cardiovascular remodeling associated with hypertension, heart failure, and atherosclerosis [1].

Angiotensin II receptor ...

Development_Hedgehog and PTH signaling pathways in bone and cartilage development [score: 1 (0%)]

Both the Hedgehog and the Parathyroid hormone receptor (PTHR) signaling pathways take part in bone and cartilage development (12082161): Parathyroid hormone-like hormone (PTHrP) stimulates osteogenic cell proliferation [1]; Sonic hedgehog homolog (SHH) ...

Development_Neurotrophin family signaling [score: 1 (0%)]

Factors of the neurotrophin family (NGF, BDNF and neurotrophins NT-3 and NT-4/5), promote neuronal survival or death. The best characterized receptors for these trophic factors are the tropomyosin-related tyrosine kinase receptors TrkA, TrkB, and TrkC, ...

Result pages: 1 2 Next

RSS	© Copyright 2013 Covance Inc. All rights reserved.