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Protein Regulatory Pathways
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Cytoskeleton remodeling_FAK signaling [score: 1 (0%)]
The biological importance of PTK2 protein tyrosine kinase 2, or Focal
adhesion kinase 1 (FAK1)-mediated signal transduction is
underscored by the fact that this tyrosine kinase plays a fundamental role in embryonic
development, in control of cell migration, cell cycle progression, and in apoptosis.
Binding ...
G-protein signaling_G-Protein alpha-12 signaling pathway [score: 1 (0%)]
Activation by ligands of G-protein coupled
receptors that interact with the trimeric G-protein alpha-12/beta/gamma
causes the exchange of GDP for GTP bound to G protein alpha subunits followed by
dissociation of the beta/gamma heterodimers. Free alpha and beta/gamma subunits are
active and ...
Inhibitory action of Lipoxins on neutrophil migration [score: 1 (0%)]
Deregulated neutrophilic inflammation and chronic infection lead to progressive
destruction of the airways in cystic fibrosis (CF). In normal tissues, lipoxins are
endogenous anti-inflammatory lipid mediators in regulation of neutrophilic inflammation
[1]. In CF, production ...
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