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Cytoskeleton remodeling_Neurofilaments [score: 1 (0%)]
Cytoskeleton of most eukaryotic cells consists of three distinct, yet interconnected,
filament systems: actin filaments,
microtubules and intermediate filaments (IF). IF network is
critically involved in cell shape control and imparts intracellular mechanical
strength.
The family ...
Development_Slit-Robo signaling [score: 1 (0%)]
Attractive and repulsive receptors regulate cell motility and attachment in axon
guidance, vascular growth, immune cell regulation and tumor progression. There is strong
evidence that development of the nervous and vascular systems is controlled by common
cues.
Semaphorins, Ephrins, SLITs ...
Role of CDK5 in neuronal cell function [score: 1 (0%)]
Cyclin-dependent kinase 5 (CDK5) is a member of the small
serine/threonine cyclin-dependent kinase family.
CDK5 is abundantly expressed in the adult brain.
Moreover, it is present in subcellular fractions enriched for synaptic membranes, and
localize to pre- and postsynaptic ...
Selected targets of SP1 [score: 1 (0%)]
Sp1 transcription factor (SP1) is a transcription factor
involved in gene expression in the early development of an organism. It belongs to the
Sp/KLF family of transcription factors. The SP1
transcription factor contains a zinc finger protein motif, by which it binds directly to
DNA ...
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