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Protein Regulatory Pathways
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Role of CDK5 in neuronal cell function [score: 1 (0%)]
Cyclin-dependent kinase 5 (CDK5) is a member of the small
serine/threonine cyclin-dependent kinase family.
CDK5 is abundantly expressed in the adult brain.
Moreover, it is present in subcellular fractions enriched for synaptic membranes, and
localize to pre- and postsynaptic ...
Selected targets of SP1 [score: 1 (0%)]
Sp1 transcription factor (SP1) is a transcription factor
involved in gene expression in the early development of an organism. It belongs to the
Sp/KLF family of transcription factors. The SP1
transcription factor contains a zinc finger protein motif, by which it binds directly to
DNA ...
Selected targets of EGR1 [score: 1 (0%)]
Early growth response 1 (EGR1) and Early growth response
2 (EGR2 (Krox20)) belong to the EGR family of C2H2-type
zinc-finger proteins, which function as a transcriptional regulators.
EGR1 activates a wide variety of different targets, which
are required for cell proliferation, ...
Selected targets of HNF transcription factors [score: 1 (0%)]
Hepatocyte nuclear factors (HNFs) are a group of phylogenetically unrelated
transcription factors that regulate the transcription of a diverse group of genes.
Hepatocyte nuclear factors are expressed predominately in the liver. However, HNFs are
also expressed and play important roles in a number ...
Selected targets of NRSF [score: 1 (0%)]
RE1-silencing transcription factor (NRSF) is a member of
the Kruppel-type zinc finger transcription factor family. It is a transcriptional
repressor of neuronal genes in non-neuronal tissues. It represses transcription by
binding a DNA sequence element called the neuron-restrictive silencer ...
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