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G-protein signaling_Regulation of RAC1 activity [score: 1 (0%)]
Regulation of Rac1 activation
Ras-related C3 botulinum toxin substrate 1 (
to the Rho subgroup of a family of small GTP-binding proteins (G-proteins) called
monomeric G-proteins. Proteins belonging to the Rho subgroup are involved in cytoskeletal
control, regulation ...
Cytoskeleton remodeling_FAK signaling [score: 1 (0%)]
The biological importance of PTK2 protein tyrosine kinase 2, or Focal
adhesion kinase 1 (
FAK1)-mediated signal transduction is
underscored by the fact that this tyrosine kinase plays ...
Cytoskeleton remodeling_Reverse signaling by ephrin B [score: 1 (0%)]
Reverse signaling by Ephrin B
Ephrin receptors and Ephrins
are both membrane bound, and following their interaction and clustering, each can
transduce signals that regulate cell responses [ 1]. Ephrin receptors activate reverse ...
Signal transduction_Calcium signaling [score: 1 (0%)]
( Ca('2+)) is a
common second messenger that regulates many processes in the cell (e.g., contraction,
secretion, synaptic transmission, fertilization, nuclear pore regulation, transcription).
In cardiac myocytes and muscle cells, Ca('2+) ...
Cytoskeleton remodeling_Integrin outside-in signaling [score: 1 (0%)]
Integrin outside-in signaling
Integrins are heterodimeric adhesion receptors composed of alpha-
and beta-subunits. It is known that at least 18 distinct alpha subunits
and 8 or more beta subunits ...
Signal transduction_PKA signaling [score: 1 (0%)]
Protein kinase cAMP-dependent (
PKA) is an enzyme playing key role
in a number of cellular processes. In its inactivated state, PKA
exists as a tetrameric complex of two catalytic ...
Cytoskeleton remodeling_Neurofilaments [score: 1 (0%)]
Cytoskeleton of most eukaryotic cells consists of three distinct, yet
interconnected, filament systems:
actin filaments, microtubules
and intermediate filaments (IF). IF network ...