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Signal transduction_AKT signaling [score: 1 (0%)]

RAC-alpha serine/threonine kinases (AKTs) are crucial mediators of various cellular process, such as apoptosis, regulation of cell cycle, protein synthesis and regulation of metabolism. The activity of AKT is modulated by various proteins, including Phosphatidylinositol-3-kinase (PI3K), Phosphoinositide-dependent ...

Signal transduction_PTEN pathway [score: 1 (0%)]

Phosphatase and tensin homolog (PTEN) is a known tumor suppressor. It inhibits growth factor-induced cell proliferation, division and regulates Integrin-mediated cell adhesion and survival [1].

PTEN antagonizes Phosphoinositide-3-kinase (PI3K), ...

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