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Cell cycle_Regulation of G1/S transition (part 2) [score: 1 (0%)]

The commencement of the cell cycle coincides with the production and the stabilization of the Cyclin D. The D-type cyclins are essential for synchronization of the cell cycle machinery with extracellular signals. [1] Expression and stability of Cyclin D is ...

Signal transduction_PTEN pathway [score: 1 (0%)]

Phosphatase and tensin homolog (PTEN) is a known tumor suppressor. It inhibits growth factor-induced cell proliferation, division and regulates Integrin-mediated cell adhesion and survival [1].

PTEN antagonizes Phosphoinositide-3-kinase (PI3K), ...

Cell cycle_ESR1 regulation of G1/S transition [score: 1 (0%)]

Estradiol induces proliferation of estrogen receptor-positive cells. ESR1 (nuclear) activated by Estradiol acts like as ligand-dependent ...

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