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Signal transduction_AKT signaling [score: 1 (0%)]
RAC-alpha serine/threonine kinases (AKTs) are crucial
mediators of various cellular process, such as apoptosis, regulation of cell cycle,
protein synthesis and regulation of metabolism. The activity of
AKT is modulated by various proteins, including
Phosphatidylinositol-3-kinase (PI3K),
Phosphoinositide-dependent ...
Signal transduction_PTEN pathway [score: 1 (0%)]
Phosphatase and tensin homolog (PTEN) is a known tumor
suppressor. It inhibits growth factor-induced cell proliferation, division and regulates
Integrin-mediated cell adhesion and survival [1].
PTEN antagonizes Phosphoinositide-3-kinase
(PI3K), ...
Selected targets of SP1 [score: 1 (0%)]
Sp1 transcription factor (SP1) is a transcription factor
involved in gene expression in the early development of an organism. It belongs to the
Sp/KLF family of transcription factors. The SP1
transcription factor contains a zinc finger protein motif, by which it binds directly to
DNA ...
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